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Vertex Pharmaceuticals, Inc. (VRTX) Yearly Returns

Year	Begining Price	Ending Price	Gain or Loss	Percent Gain or Loss
1992	14.75	9.75	-5.00	-33.90%
1993	9.75	18.50	8.75	89.74%
1994	18.50	15.00	-3.50	-18.92%
1995	15.00	26.50	11.50	76.67%
1996	26.50	40.25	13.75	51.89%
1997	40.25	33.00	-7.25	-18.01%
1998	33.00	29.75	-3.25	-9.85%
1999	29.75	35.00	5.25	17.65%
2000	35.00	143.00*	108.00	308.57%
2001	71.50	24.59	-46.91	-65.61%
2002	24.59	15.85	-8.74	-35.54%
2003	15.85	10.35	-5.50	-34.70%
2004	10.35	10.57	0.22	2.13%
2005	10.57	27.67	17.10	161.78%
2006	27.67	37.42	9.75	35.24%
2007	37.42	23.23	-14.19	-37.92%

*The 2000 ending price for Vertex has been adjusted for a 2 for 1 stock split.